Can LDN treat chronic skin conditions
The opioid-blocker naltrexone might prove effective in treating several chronic inflammatoryskin diseases , according to the several reviews of reports, case series, and random trials. With ranging evidence, oral low-dose naltrexone proved successful in managing Hailey-Hailey disease, lichen planopilaris, and pruritus associated with scleroderma. As reported by Natasha Atanaskova of the University of California Irvine, and her colleagues: " Naltrexone , particularly in low doses, has the potential to treat an array of primary skin lesions through inflammatory and immune-cell regulation and skin regeneration" and "Potential future uses include the treatment of diabetic wounds, bullous diseases, scarring alopecia, alopecia areata, and psoriasis." Clinical evidence: The researchers analyzed 22 articles, which involved randomized clinical trials, case series, and reports. Of the articles evaluated, 14 included high-dose naltrexone , 7 were dedicated to low-d...