What Do You Need To Know About Migraines?
Throbbing pain in the head, sensitivity to light and sound, nausea, it sounds like you may have a migraine. A headache is described simply as constant pain in the head. While a migraine, on the other hand, is defined as a recurrent throbbing headache that generally affects one side of the head and is often accompanied by nausea and disturbed vision. Migraines are not just simple pains in the head, but they can bring visual disturbances, nausea, vomiting, dizziness, extreme sensitivity to sound, light, touch, smell, etc.
Significance Of Migraine
According to the Migraine
Research Foundation, migraines are
exceptionally prevalent, being the 3rd most common illness in the world.
Approximately 39 million people, including children, are affected by migraines
in just the United States. Migraine is a more common problem among
women than men and usually affects people between 18 and 44, although people of
any age can suffer from these irritating headaches.
Types Of Migraine
There are primarily two types of migraine:
- complicated migraine
(with aura)
- common migraine
(without aura)
Aura describes specific symptoms that refer to neurological
disturbances, such as bodily weakness and visual disturbances. However, migraine
headaches can be further
classified depending on symptoms. For instance, a person who suffers a migraine
each month for at least 15 days could be diagnosed with chronic migraine.
Cluster headaches, another possible
type of migraine, may have similar symptoms. These don't usually last as
long as a migraine but can be more painful. These intense headaches
can involve radiating, almost burning pain that may make your eyes swell and
possibly even your nose run. Cluster headaches are so powerful that they
have garnered the name "suicide headaches."
Symptoms Of Migraine
Migraine usually causes a pulsing
sensation or a throbbing pain on one side of the head; however, migraine may
also be experienced on both sides of the head. Migraine attacks may last
for a few hours to several days, and the pain can be sufficiently intense to
interfere with your daily activities. Other symptoms typically accompany it.
- Nausea
and vomiting
- Sensitivity
to light, noise, and smell
- Upset
stomach
- Abdominal
pain
- Loss
of appetite
- Hot
flashes or cold (chills)
- Pale
skin color
- Feeling
tired
- Dizziness
- Blurred
vision
- Tender
scalp
- Tingling
or numbness in the extremities or face
- Diarrhea,
in rare cases
- Fever,
in rare cases
Causes Of Migraine
Even though a significant amount of research has understood
migraines, a specific cause is not always known. Both genetics and other
environmental factors play a role in the underlying factors. Most people
dealing with migraines regularly are able to point out certain triggers
that seem to be associated with their severe headaches.
Migraine Triggers
- Hormonal
changes in women
Imbalances in estrogen, such as before or during menstrual
periods, pregnancy, and menopause, seem to trigger headaches in many
women.
- Hormone
imbalances in the brain
Any changes in the brainstem and its relations with the trigeminal
nerve, a major pain pathway, might be involved. Imbalances of chemicals in the
brain chemistry, e.g., serotonin imbalance, suspect migraines treatment, as it
helps regulate pain in your nervous system.
- Medications
Medications including oral contraceptives and vasodilators, such
as nitroglycerin, can aggravate migraines with aura. However, some women also
state that they find relief in their migraines when taking these
medications.
- Drinks
Migraines may be caused or
worsened by using alcoholic beverages, especially wine, and drinks containing
too much caffeine, such as coffee.
- Stress
Any type of stress can cause migraines.
- Sensory
stimuli
Sometimes, your body may respond to bright or flashing lights and
loud sounds by inducing migraines. Moreover, strong smells such as
perfume, paint thinner, secondhand smoke, and others can also trigger migraines
in some people. We can conclude by saying that over-stimulation of any senses
can result in migraines.
- Changes in
sleep patterns
Getting too much or too little sleep can trigger migraines
in some people.
- Physical
factors
Migraines can be provoked by
intense physical exertion such as sexual activity.
- Weather
changes
A variation in weather or barometric pressure can trigger a
migraine.
- Foods
Foods that underwent processing or aging might trigger
migraines. The same is the case with very sugary and salty foods. Foods
containing additives like sweetener aspartame and the preservative monosodium
glutamate (MSG) can provoke migraines. Also, skipping meals can cause severe
migraines too.
Risk Factors
Numerous factors make you more prone to having migraines,
such as:
- Family
history
Having the problem of migraines in people in your family
means that you have a good chance of experiencing it yourself. As far as
genetics go, a child with two migraine-suffering parents has a 75
percent chance of being a migraine sufferer.
- Age
A person of any age can develop migraines, though the first
usually occurs during adolescence. Migraines tend to reach their peak
during the 30s and gradually become less intense and less common in the
following decades.
- Gender
Women develop migraines thrice as common as men.
- Hormonal
changes
Women with migraines would probably experience headaches
shortly after or before menstruating. It is mainly because of the fact that
estrogen levels fluctuate during menstruation, pregnancy, or even menopause.
However, these start to get better after menopause generally.
Treating Migraines
Through Ketamine
Ketamine is a medication that has
been used for anesthesia for decades now. It is a dissociative anesthetic as it
brings sedation more quickly as compared to other similar medications. Although
it is mainly used for relaxing or sedation if used in high doses, using them in
low doses can help relieve severe pain efficiently.
Ketamine medication produces an
analgesic effect without having to do anything with opiate receptors in the
brain like opioid pain medications. As a matter of fact, ketamine has
been used instead of opioids to help reduce pain after surgeries or similar
painful procedures. Ketamine has an effect on the N-Methyl-D-aspartic
acid (NMDA) receptors in the brain, so it acts as a signaling molecule to
manage pain. The drug has naturally gained prevalence in treating untreatable
pains such as migraine.
Ketamine Nasal Spray
A number of studies have successfully examined ketamine for
its functioning against specific types of chronic pains, including migraines.
A study in 2012 found that patients who took part in the research and
received ketamine infusions intravenously experienced pain reduction
significantly. Another study in 2013 concluded that intranasal ketamine
helped people with migraine with prolonged aura.
In 2017, a study involving 61 patients with migraine showed that 75 percent
of them experienced improvements within a week of usage of ketamine infusion
therapy. Moreover, their pain intensity on a scale of 1 to 10 fell from 7.5
at admission to 3.4 on discharge. All these patients did not see any
improvements in their condition with other treatments.
In 2019, researchers examined the efficacy of intranasal ketamine for children.
The patients experienced a collective 66 percent reduction in migraine pain
when each of them was given intranasal ketamine doses.
Get Ketamine Nasal Spray from Harbor
Compounding Pharmacy
With the strong offerings of ketamine to help migraine sufferers,
more patients have now begun to note this medication. If you are one of those
sufferers of migraine and are looking to find eternal relief, please
contact us at Harbor Compounding Pharmacy. Our talented pharmacists will
work with you and your doctor to determine if intranasal ketamine could
be right for you.
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